weak or shallow breathing; blue appearance of the skin; or. severe anxiety, unusual fear or uneasy feeling. Common side effects of lidocaine injection may include: drowsiness, dizziness; nausea, vomiting; feeling hot or cold; confusion, ringing in your ears, blurred vision, double vision; or. numbness in places where the medicine is ...* Low systolic blood pressure (BP) for children is defined as less than 70 mmHg from one month to one year, less than (70 mmHg + [2 × age]) from one to 10 years, and less than 90 mmHg from 11 to 17 years. PEF Peak expiratory flow ... Thus, IM injection of epinephrine into the anterior lateral thigh is the preferred route of delivery for ...Background: The process of aspiration has been ingrained in the intramuscular injection procedure, and whilst many policies no longer recommend this practice, it often continues to be taught and practiced. The result is a variation in this procedure not always consistent with an evidence-based approach. Design: A systematic literature review.Django Unchained. There's a striking shot in the trailer for Django Unchained where a sharp-shooting Jamie Foxx blasts an evildoer off his horse, spraying the cotton fields with blood in extreme ...Appropriate needle size and angle of insertion helps ensure that medication is injected into the subcutaneous tissue without harm to underlying muscle mass, nerves, or bone. 9. No-pinch method: Use a 1 ⁄ 2 - to 5 ⁄ 8 -inch needle. 8. Hold gauze between the third and fourth fingers of the nondominant hand.A firm pressure, without rubbing, at the injection site should be maintained 2 to 5 min after. 5. The aim of our study was to evaluate the risk of bleeding events at the site of injection following IM vaccination in patients treated with therapeutic anticoagulation.Blood, a specialized colloidal bodily fluid within the circulatory system, is a complex composition of blood cells and plasma. Blood accounts for approximately 8% of the body weight, with an average density of approximately 1,060 kg/m 3. The average adult has from about 4–5 l (female) and up to 5–6 l (male) of blood.After signing the consent form, the subjects were randomly assigned to receive two intramuscular injections of 1 ml of either Sustanon® 250 (30-mg TP, 60-mg TPP, 60-mg TI, and 100-mg TD per ml) (n = 9) or placebo (n = 10), separated by 3 weeks. Fingerprick DBS samples were collected twice pre-injection, at least 5 days apart, and on days 1, 3 ...Introduction. Intramuscular injection (IMI) is a common clinical procedure with 16 billion injections administered globally every year [] in a wide variety of healthcare settings [].The widespread use of IMI reflects the range of medications that can be delivered via this route including sedatives, hormonal therapies, vaccines, tumour immunotherapy, …It happens on occasion, no biggie. As long as it's not shooting out blood, you should be okay. Sounds like you were clear and careful with the injection. I do IM and I have never had blood "shoot out", meaning like go in the air. I have had a lot of blood build up on the injection site and start to pool there.The deltoid is the preferred site for intramuscular injection (IMI) because of its easy accessibility for drug and vaccine administration. Government immunization advisories, standard anatomy textbooks, and researchers have proposed various injection techniques and sites, but specific guidelines are lacking for the administration of IMIs in …A single intramuscular injection of 500 or 1000 µg. of hydroxocobalamin to 17 individuals resulted in a 1.8- to 4.1-times higher mean serum vitamin B 12 blood level, respectively, 5 hours after injection; a 4.6- and 12.8-times higher level 24 hours after injection; a 2.4- and 5.2-times higher level 72 hours after injection, and a 1.6- and 2.4-times higher level by …A randomized clinical trial with a single vitamin K administration of 0.5 mg IM, 0.2 mg IM, or 0.2 mg IV at birth in 38 preterm infants showed that the serum vitamin K levels of all preterm infants were elevated above the normal range on day 5 but declined day 25, particularly in those who received IV vitamin K supplementation at birth .... injection for 4–6 months) to get the changes of puberty started. Girls might get low doses of estrogens for 4–6 months to start breast development. After ...The sciatic nerve is the most commonly injured, and frequently the resulting muscle weakness and associated disability are irreversible. This case report includes a video of a patient with foot drop 6 weeks after gluteal intramuscular injection. Such injuries can be prevented by proper awareness and training, the implementation of safer ...The feasibility of a long-term control of the systemic delivery of Epo after a single intramuscular injection may have implications for the development of gene therapy protocols for patients with β-thalassemia. ... Stable gene transfer and expression of human blood coagulation factor IX after intramuscular injection of recombinant adeno ...The appropriate needle gauge and length are determined by a number of factors, including the target tissue, injection formulation, and patient population. For example, venipuncture requires the use of needles typically as large as 22-21 gauge inserted to depths of 25-38 mm to withdraw milliliters of blood. 3 In contrast, vaccines usually ...Temporary side effects of cortisone knee injections include localized pain, elevated blood sugar, facial redness and whitening of skin around the injection site, explains About.com...First, most especially with the pen devices, once you have injected the medication into the skin, count to five before removing the needle. Second, apply gentle pressure with a gauze pad over the injection site as you remove the needle from your skin, and hold it for about 10 seconds. The gauze helps seal the punctured tissue and prevents leakage.Mar 10, 2011 · Flotte et al. 14 demonstrated that rAAV1 vector genomes can be detected in mouse and rabbit blood up to 90 days after IM injection of doses ⩾ 1E13 vg kg −1 (40–2000-fold higher doses than ...Abstract. Antimicrobial agents are usually administered to cattle intramuscularly (im). After im injections, tissue damage at the injection sites may occur. This may be caused by the vehicle, the active ingredient, or both. Other factors affecting tissue reaction are pH, osmotic status, injection volume, concentration of the antimicrobial agent ...A man brewed a tea from " magic mushrooms " and injected the concoction into his veins; several days later, he ended up at the emergency department with the fungus growing in his blood. The man ...It makes the insulin you take work better, and it removes the sugar, or glucose, from your blood. It also helps you lose weight, which can lower blood sugar. Try to build up to at least 30 minutes ...Dec 18, 2020 ... Then many years later at the age of 21, the patient became pregnant and the keloid scar went through another growth spurt, but a rather ...Flotte et al. 14 demonstrated that rAAV1 vector genomes can be detected in mouse and rabbit blood up to 90 days after IM injection of doses ⩾ 1E13 vg kg −1 (40-2000-fold higher doses than ...Obese women had markedly lower C max, AUC, and average concentration (C av) of hCG as compared with normal-weight women after SC injection (all P<0.05); however, the pharmacokinetic parameters were similar for normal-weight and obese women after IM injection. Citation 98 Thus, IM route may be more suitable for obese women who would receive hCG.Compared to baseline, blood glucose significantly (p=0.012) elevated 1 day after steroid injection but not 2 days after injection. In the HbA1c >7% and insulin groups, blood glucose was significantly increased 1 day after injection compared to that in the HbA1c ≤7% (p=0.011) and non-insulin (p=0.024) groups, respectively.Takeaway. Vaginal bleeding after sex can be caused by dryness, tearing, an infection, or a growth in the uterus, such as cancer or polyps. Many people with vaginas experience vaginal bleeding ...smj67. 11 Posts. May 25, 2005. That's happened to me a few times and the answer I got was the needle probably went thru a vein to the other side and out the far wall of the vein and embedded in muscle tissue so when you aspirated there was no blood, but after the injection and withdrew the needle back through the vein the blood following the ...The IM injection route deposits medication into deep muscle tissue, which has a rich blood supply, allowing medication to be absorbed faster than it would be by the subcutaneous route. This rich blood supply, however, increases the risk for injecting drugs directly into blood vessels. Any factor that interferes with local tissue blood flow ...Intramuscular administration of vitamin K for prevention of vitamin K deficiency bleeding (VKDB) has been a standard of care since the American Academy of Pediatrics recommended it in 1961. Despite the success of prevention of VKDB with vitamin K administration, the incidence of VKDB appears to be on the rise. This increase in incidence of VKDB is attributable to parental refusal as well as ...The time to reach therapeutic concentrations (5 or 10 mg L −1) after a single intramuscular TXA 1 g injection are 4 or 11 min, with the time above these concentrations being 10 or 5.6 h ... Although we attempted to obtain a blood sample 10 min after the i.v. injection, because patient care was the priority, in many cases this was not possibleHerein, the bioavailability of hCG was compared after intramuscular (i.m.) or subcutaneous (s.c.) injection in obese and non‐obese women. METHODS: Twenty four Chinese women, 12 with a body mass index (BMI) ≥28 kg/m 2 and 12 with a BMI of 20–25 kg/m 2 were recruited as the obese and non‐obese groups respectively.This is why it was enormous validation when I finally visited a geneticist earlier this year, who revealed after a thorough two-hour evaluation that I had Type III of a rare connective tissue disorder known as Ehlers-Danlos syndrome, or EDS. EDS is characterized by hypermobile joints and a deficiency in collagen (connective tissue) that results ...Select the appropriate site for your injection. Stand in an appropriate and safe position in case the horse reacts to the needle being inserted. Quickly and decisively, insert the needle perpendicular to the skin. A fast stab is less painful for the patient. The entire length of the needle, up to the hub, should be inserted into the muscle.The most common route of vaccine administration is SC or IM injection. This approach is excellent for small numbers of animals and for diseases in which systemic immunity is important. In addition, the veterinarian can be sure an animal has received the appropriate dose of vaccine. However, local immunity is sometimes more important than ...May 6, 2024 · Open the alcohol wipe: Wipe the area where you plan to give the injection. Let the area dry. Do not touch this area until you give the injection. Prepare the needle: Hold the syringe with your writing hand and pull the cover off with your other hand. Place the syringe between your thumb and first finger.Incorrect intramuscular injections can be caused by a variety of factors, including improper site selection, inappropriate needle length, and incorrect injection technique. These errors may lead to complications such as pain, infection, tissue damage, or suboptimal medication absorption, highlighting the importance of precise adherence to ...We would like to show you a description here but the site won't allow us.That sounds like a bit more than usual bleeding. A little bleeding is normal. There are lots of little capillaries that can get "scratched" when you inject. (By the way, the dorsogluteal site is not recommended or taught in nursing school anymore. Too much risk for injury to the sciatic nerve.Introduction. Peripheral nerve injury after injection is a common, though usually transient, phenomenon. Sciatic neuropathy is the most commonly reported, but most injections, including vaccinations, carry some degree of risk [].Development of complex regional pain syndrome (CRPS) after an injection, however, is uncommon, and its variable manifestations may delay the diagnosis and subsequent ...signs of a blood clot - sudden numbness or weakness, severe headache, chest pain, sudden cough, coughing up blood; problems with vision or speech, swelling or pain in an arm or leg. Common Depo-Provera side effects may include: changes in your menstrual periods; weakness, feeling tired; stomach pain; feeling nervous;Nov 10, 2019 · In addition, the quads are very nerve dense and it is far more likely that you will hit a nerve and cause muscle twitching during a quad injection. Also, if you get post-injection pain (PIP) in your quad, you severely inhibit your ability to function as you need to limp around on your leg and it can significantly impede simple day to day ...How to Give the IM Injection. To give an IM injection: Make sure you have the right amount of the right medicine in the syringe. Wash your hands well with soap and water. Dry them. Carefully find the spot where you will give the injection. Clean the skin at that spot with an alcohol wipe.Apply steady, firm pressure for 5 minutes. If the wound is small, use your fingers. If the wound is big, use your palm. If the bleeding continues for 10 minutes, place an additional cloth on top ...Abstract. Intramuscular (IM) injections are a well-established method of delivering a variety of therapeutics formulated for parenteral administration. While the wide range of commercial IM pharmaceuticals provide a wealth of pharmacokinetic (PK) information following injection, there remains an inadequate understanding of drug fate at the IM ...Intramuscular (IM) injections deposit medications deep into the muscle tissue. Since muscle fibers are well perfused, this route of administration provides quick uptake of the medication and allows for the administration of relatively large volumes. Skeletal muscles have fewer pain-sensing nerves than subcutaneous tissue, which allows for the ...BLOOD SPURTS definition | Meaning, pronunciation, translations and examplesApr 10, 2021 · Apply steady, firm pressure for 5 minutes. If the wound is small, use your fingers. If the wound is big, use your palm. If the bleeding continues for 10 minutes, place an additional cloth on top ...The deltoid is the preferred site for intramuscular injection (IMI) because of its easy accessibility for drug and vaccine administration. Government immunization advisories, standard anatomy textbooks, and researchers have proposed various injection techniques and sites, but specific guidelines are lacking for the administration of IMIs in …The main precaution when administrating an IM injection is to avoid entering a blood vessel (especially an artery), which could lead to the infusion of a toxic agent or a toxic vehicle directly into the intravascular space. This can usually be prevented if, immediately after inserting the needle into the muscle, the plunger is gently pulled back.Percutaneous coronary intervention (PCI) involves angioplasty and often stenting. After this procedure, there is a chance that a blood clot will form at the blockage site. A blood clot can also form on a stent if you have one. Your healthcare provider will prescribe medicine to help prevent this. Over time, the artery may also become blocked again.Now stretch the skin flat. Hold the syringe at a 90-degree angle to your skin so it's standing straight out— right above the place where you'll give the shot. Quickly insert the needle all the way into the flattened skin. Now, if your doctor told you to, you'll need to look for blood in the syringe before you inject the medicine. Here's how.The purpose of this study was to investigate the technique registered nurses (RNs) use during IM injections and incidence of blood aspiration. This descriptive study surveyed 164 RNs. Results noted that 74% of the sample continue to aspirate at least 90% of the time. Of the participants who continue to aspirate, only 3% aspirate for the ...In contrast, venous bleeding tends to be under much lower pressure and less disseminated. However, blood projected from ruptured varicose veins of the lower limbs may also result in a similar pattern of projected, disseminated fine bloodstains. Two cases of lethal haemorrhage from lower leg varicosities are presented involving a 60-year-old ...A randomized clinical trial with a single vitamin K administration of 0.5 mg IM, 0.2 mg IM, or 0.2 mg IV at birth in 38 preterm infants showed that the serum vitamin K levels of all preterm infants were elevated above the normal range on day 5 but declined day 25, particularly in those who received IV vitamin K supplementation at birth .The American Cancer Society and the National Lymphedema Network both recommend having blood pressure taken using a manual cuff and stethoscope. This avoids the high pressure squeezing that happens with a blood pressure machine, which often occurs a few times before giving a reading. Many organizations recommend using the thigh to take blood ...The incidence of nerve injury and aseptic tissue necrosis is, to the best of the authors' knowledge, not described for equids in scientific studies, whereas hematomas after injections occur infrequently. The predominant complications after IM injections are edema, cellulitis, and abscess formation, often causing hindrance in movement [7].Concentrations of lignocaine in the blood after intravenous, intramuscular epidural and endotracheal administration Anaesthesia . 1961 Oct;16:461-78. doi: 10.1111/j.1365-2044.1961.tb13426.x.Signs of delayed puberty in boys include: the penis and testicles not starting to grow larger by age 14; genital growth that takes longer than 5 years; short ...l Injuries to nerves and blood vessels (Small, 2004); l Inadvertent intravenous access. These complications can be avoided if the site for injection is accurately identi-fied and a skilled evidence-based tech-nique is used (Greenway, 2014). Evidence base The procedure for IM injection has been dis - cussed widely in the literature but there areIf you see blood in the bottom of the syringe (hub) before you push in the plunger: Remove the needle without giving the medicine. Dispose of the needle in a safe way. Use a hard plastic, metal, or "sharps" container with a lid. Use a new needle to give the shot. You can put a new needle on the syringe and then give the injection in a new spot.IM injections in the deltoid muscle are not recommended for children 12 months of age and younger.1. Table 1: Needle selection guidelines for IM injections in the deltoid muscle using needle gauge 22-25 for children >12 months to 12 years of age. Table 2: Needle selection guidelines for IM injections in the deltoid muscle using needle gauge 22 ...Abstract. Intramuscular pressure and muscle blood flow was measured in the supraspinatus muscle in 6 healthy subjects. The recordings were performed at rest, during isometric exercise, during an isometric muscle contraction of 5.6 kPa (42 mm Hg) and 10.4 kPa (78 mm Hg) and at rest after the contraction. Intramuscular pressure was measured by ...A small blood vessel that bursts during ejaculation, like how you might get a nosebleed after blowing your nose. Trauma from a medical procedure on your urinary or reproductive systems, such as a vasectomy or biopsy on your prostate. You may see blood in your semen for over a week after a vasectomy or up to four weeks after a prostate biopsy.diarrhea, watery and severe, which may also be bloody. difficulty with breathing. difficulty with swallowing. dizziness. fast, irregular, pounding, or racing heartbeat or pulse. feeling of discomfort. feeling of warmth. fever with or without chills. general body swelling.Myth: Patients should wait at least 24 hours before bathing or swimming after undergoing a needle-based interventional spine procedure (i.e., epidural steroid injection, intra-articular injection, medial branch block, radiofrequency ablation). Fact: There is no clear evidence that bathing, swimming, or use of hot tubs after a needle-based ...Weakness on 1 side of the body, trouble speaking or thinking, change in balance, drooping on one side of the face, or blurred eyesight. Shortness of breath, a big weight gain, or swelling in the arms or legs. Trouble walking. Very bad dizziness or passing out.Blood is mandatory to maintain adequate circulation, provide nutrients, and remove waste from the brain, vital organs, and tissues.[1] A hemorrhage is the loss of blood components from the cardiovascular system. Hemorrhagic shock occurs when this blood loss leads to inadequate tissue oxygenation. Hemorrhage secondary to traumatic injury is the leading cause of death of Americans from one to 46 ...Buzzy is known to be effective in reducing pain during IM injections, IV catheterization, 29 immunization, 6, 7 and blood sampling. 30, ... 15 children and parents were excluded from the study, as they did not want to evaluate the fear and pain scales after IM injection (Figure 2, incomplete data collection). Although they initially accepted to ...Objective: To compare the outcomes for patients with chronic plantar fasciitis after extracorporeal shockwave therapy (ESWT) or autologous blood injection (ABI). Design: Cohort study-retrospective analysis of prospectively collected data. Setting: Hospital-based Sports Medicine Outpatient Clinic. Patients: One hundred two consecutive patients with chronic plantar fasciitis, treated with either ...The medicine needs to go into muscle. You do not want to hit a nerve or a blood vessel. So show your health care provider how you will choose where you will put the needle, to make sure you can find a safe spot. Thigh: The thigh is a good place to give an injection to yourself or a child less than 3 years old.slurred speech. sudden loss of coordination. sudden, severe weakness or numbness in the arm or leg. sweating. swelling of the fingers, hands, feet, or lower legs. tightening of your throat. unusual bleeding or bruising. unusual tiredness or weakness. vision changes.After intramuscular injection of AAV-F.IX into immunocompetent C57BL/6 mice, hF.IX was detected either transiently or not at all in the plasma of injected animals (Fig. 1). When the same plasma samples were tested for antibodies against hF.IX, a strong antibody response was seen in all injected animals starting at day 11 postinjection (Fig. 2 A ...Urine samples and blood samples were collected twice pre-treatment, at least 5 days apart, and on days 1, 3, 5, 10 and 14 post-injections to assess steroidal and haematological biomarkers of the ABP. The steroidal profile was flagged suspicious in all Sustanon®-treated subjects, whereas the haematological profile was flagged suspicious in six ...We sought to determine whether intramuscular injection of a recombinant adeno-associated virus (rAAV) vector expressing human factor IX (hF.IX) could direct expression of therapeutic levels of the transgene in experimental animals. High titer (10(12)-10(13) vector genomes/ml) rAAV expressing hF.IX w …Results. Observations of mild to moderate adverse events in our clinical work with MC3 17 and data showing slow MC3 clearance after IV administration 23 fueled a hypothesis that the adverse events might be related to the extended presence of MC3 at the injection site. Mass spectrometry analysis of muscle tissue revealed that, 24 h after IM …The mRNA vaccine route from injection site to critical immunologic tissues, as well as the localization of protein antigen following intramuscular (i.m.) administration, is crucial to generating an effective immune response. Here, we quantified mRNA at the injection site, lymph nodes, and in select tissues. mRNA was primarily present 24 h after ...Objective: The pharmacokinetics and efficiency of human chorionic gonadotropin (hCG) after subcutaneous (SC) injection was to clarify in comparison with the intramuscular (IM) mode of administration. Design: In a prospective study, the pharmacokinetics of hCG and the response of serum testosterone (T), luteinizing hormone (LH), and follicle-stimulating hormone (FSH) after an IM and SC ...Push down on the plunger to push the air into the bottle (Image 1). Leave the syringe in the bottle. Now turn the bottle upside down so that the bottle is on top and the syringe is on the bottom (Image 2). Make sure that the tip of the needle is below the level of the liquid in the bottle. Pull back on the plunger.An injection site reaction is your body's response to an immunization or other injection at the site where it was administered. It typically manifests as swelling, pain, rash, redness, or bleeding. Injection site reactions are usually caused by an immune response to the needle, vaccine, or other medicine. These types of reactions are typically ...In addition, the quads are very nerve dense and it is far more likely that you will hit a nerve and cause muscle twitching during a quad injection. Also, if you get post-injection pain (PIP) in your quad, you severely inhibit your ability to function as you need to limp around on your leg and it can significantly impede simple day to day ...It typically manifests as swelling, pain, rash, redness, or bleeding. Injection site reactions are usually caused by an immune response to the needle, vaccine, or other medicine. These types of reactions are typically mild and resolve in a day or two without treatment. Less commonly, injection reactions are due to an infection or allergy.After you inject and withdraw the needle from the muscle, activate the safety device on the needle using a hands-free method immediately. ... SIRVA causes shoulder pain and limited range of motion within 48 hours after IM vaccine administration. 10,11 Experts advise immunizers to avoid administering vaccines in the top one-third of the …An intragluteal IM injection is when a medication is injected into a muscle in your buttocks (butt). An intragluteal IM injection is a way to give medication directly into a deep muscle in your buttock. Your healthcare provider will explain which medication you’re getting and why. In the past, we gave intragluteal IM injections in the thick ...Aluminium (Al) toxicokinetics after intramuscular (IM) injection of Al-adjuvanted vaccines is unknown. Since animal data are required for modeling and extrapolation, a rat study was conducted measuring Al in plasma and tissues after IM injection of either plain Al-hydroxide (pAH) or Al-phosphate (pAP) adjuvant (Al dose 1.25 mg), single human doses of three Al-adjuvanted vaccines (V1, V2, and ...In females, delayed puberty is the lack of breast development by 13 years, a delay of over 4 years between thelarche and completion of puberty, or a lack of menarche by 16 years. In males, a pubertal delay is evident by a lack of testicular enlargement by 14 years or more than 5 years between testicular enlargement and completion of puberty. [1]Blood typically exits the wound in spurts, rather than in a steady flow; the blood spurts out in time with the heartbeat. The amount of blood loss can be copious, and can occur very rapidly. Venous bleeding: This blood is flowing from a damaged vein. As a result, it is blackish in colour (due to the lack of oxygen it transports) and flows in a ...Jan 30, 2024 · A small blood vessel that bursts during ejaculation, like how you might get a nosebleed after blowing your nose. Trauma from a medical procedure on your urinary or reproductive systems, such as a vasectomy or biopsy on your prostate. You may see blood in your semen for over a week after a vasectomy or up to four weeks after a prostate biopsy.DNA extracted from white blood cells (WBCs) was tested to determine whether WBCs can be collaterally transfected by plasmid or transduced by rAAV vectors in this context, and can be used as a surrogate marker for gene doping. ... We demonstrate that IM injection of a conventional plasmid and rAAV vectors results in the presence of DNA that can ...Did an injection about 20 mins ago, it was a bit more painful compared to my usual injections... however, when I pulled the needle out, an intense amount of dark blood came down my leg and onto the floor. It stopped shortly after I …Open the alcohol wipe: Wipe the area where you plan to give the injection. Let the area dry. Do not touch this area until you give the injection. Prepare the needle: Hold the syringe with your writing hand and pull the cover off with your other hand. Place the syringe between your thumb and first finger.Most IM shots are given to adult horses with a 1 1/2-inch needle so that the medication is injected deep into the muscle mass. Foals are usually given IM injections with a 1-inch needle. ... nerves or blood vessels. Also, the injection site should allow the handler to be in a relatively safe position if the horse objects to the injection.. If you see blood in the syringe, it means you might have hitincreased growth of face or body hair. headache. Ativan (Injectable) received an overall rating of 8 out of 10 stars from 574 reviews. See what others have said about Ativan (Injectable), including the effectiveness, ease of use ... Introduction. Postpartum hemorrhage (PPH), defined by th Serious reactions to intramuscular injections are rare; in one series of 26 294 adults, of whom 46% had received at least one intramuscular injection, only 48 (0.4%) had a local adverse effect. 4 However, subcutaneous injections can cause abscesses and granulomas. 1,5,6 Muscle is probably spared the harmful effects of substances injected into ... WHO Library Cataloguing-in-Publication Data WH...
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